Equity Profile

TWST

TWIST BIOSCIENCE COR

Health CareBiotechnology$4.3B

May4Mon

Post-Earnings Recap

ReportedQ2-2026Pre-Market7:21 AM EDT

Twist Bioscience Misses on EPS, Stock Down 6.97%

Metric	Actual	Expected	Surprise
EPS	$-0.71	$-0.53	-31.48%
Revenue	N/A	$108M	N/A

management commentary, guidance changes, and full analysis available with Pro.

Twist Bioscience Misses on EPS, Stock Down 6.97%

Key Numbers

Metric	Actual	Expected	Surprise
EPS	$-0.71	$-0.53	-31.48%
Revenue	N/A	$108M	N/A

Management Commentary

Tone: Unknown

No transcript is on record for this earnings call, so the analysis is based solely on numerical results.

What It Means

Twist Bioscience's earnings report showed a larger-than-expected loss per share, which contributed to a 6.97% decline in stock price. The lack of revenue figures and guidance may raise concerns among investors about the company's future performance. Overall, the disappointing EPS result indicates potential challenges ahead for the company.

Company Snapshot

Twist Bioscience Corporation is a biotechnology company that specializes in DNA synthesis and gene editing technologies. Operating in the health care sector, Twist aims to enable advancements in fields like synthetic biology, pharmaceuticals, and diagnostics, making it a key player in the evolving biotech landscape.

Key Metrics to Watch

Earnings Per Share (EPS)

EPS is a crucial indicator of the company's profitability and financial health, helping investors gauge performance against expectations.

$-0.53

Revenue

Revenue reflects the company's ability to generate sales and is essential for assessing growth and market demand for its products.

$108M

Wall Street expectations, options signals, track record, and call prep available with Pro.

Original Pre-Earnings Preview

Context

Company Snapshot

Earnings Scorecard·Last 8Q

EPS Beat Streak

EPS Beat Rate

38%

Avg EPS Surprise

+5.33%

Avg Stock Reaction

-3.48%

Last Quarter Recap

In Q1-2026, Twist reported an EPS of $-0.50, which was a slight miss compared to the estimate of $-0.47. Following the earnings report, the stock saw a positive reaction, gaining nearly 14% the next day.

Management Promises & Guidance

Expectations

Wall Street Expectations

Analysts expect Twist to report a loss of $-0.53 per share on revenues of $108 million for Q2-2026. The market is closely watching these figures to assess the company's growth trajectory.

Bull Case

If Twist can exceed the revenue expectations and show signs of improving margins, it could signal a turnaround in its financial performance, leading to a positive stock reaction.

Bear Case

Conversely, if the company fails to meet revenue expectations or reports a wider loss, it could raise concerns about its growth strategy and lead to a negative market reaction.

Key Metrics to Watch

Earnings Per Share (EPS)

$-0.53

EPS is a crucial indicator of the company's profitability and financial health, helping investors gauge performance against expectations.

Revenue

$108M

Revenue reflects the company's ability to generate sales and is essential for assessing growth and market demand for its products.

Expectations

Two Questions That Matter

The print will turn on these two things.

Will Twist's revenue meet or exceed the consensus estimate of $108 million?

Revenue performance is critical for assessing the company's growth and market demand, which will heavily influence investor sentiment.

What specific strategies is management implementing to improve EPS, currently estimated at $-0.53?

Understanding management's approach to improving profitability is essential for evaluating the company's future potential and operational efficiency.

Edge

What the Street Is Missing

Why consensus could be wrong

The Street may be underestimating Twist's potential for revenue growth due to its innovative product offerings and expanding market presence.

Supporting Evidence

Despite recent misses, Twist's technology pipeline suggests potential for significant revenue increases not reflected in current estimates.

The options market is pricing in a larger move than historical averages, indicating that traders expect a more substantial shift in stock price than the consensus suggests.

Key Risk

If Twist's revenue growth exceeds $108 million, it could challenge the current bearish sentiment and shift investor expectations.

Edge

Thesis-Break Levels

Pre-commit to what would confirm each case.

This quarter, the debate centers around whether Twist can demonstrate solid revenue growth and a path to profitability amid ongoing market challenges.

Bull Confirmed If

Revenue growth exceeding $108 million with a reduction in EPS loss to below $-0.50 would confirm the bull case.

Bear Confirmed If

A revenue miss below $107 million or an EPS loss greater than $-0.53 would confirm the bear case.

Pre-Earnings Positioning

Options Market

Implied Move

±15.73%

Historical Avg

±10.2%

Pricing rich

The options market is pricing in a significant move of about 15.73%, indicating that investors expect volatility around the earnings announcement.

Options are pricing ±15.7% while TWST has averaged ±10.2% over the last 8 prints — setup is pricing rich.

Detail

ATM IV

1.1%

30d HV

75.0%

Calls (18K)P/C Ratio: 0.40Puts (900)

Edge

Insider Activity

Open-market trades by officers, directors, and 10%+ holders over the trailing 90 days.

Bought

$0.00

0 sh

0 insiders

Sold

$1.2M

19,268 sh

2 insiders

Net

$1.2M

Net selling

Most Active Insiders· 6 open-market trades

Chief Executive OfficerLeproust Emily M.
$630,957.35

Preparation

Post-Print Playbook

Likely market behavior by outcome — not investment advice.

Beat & Raise

If Twist beats expectations, history suggests a positive stock reaction, averaging a 0.72% increase the following day, confirming a bullish outlook.

In-Line / Cautious

If results are in line with expectations but management's commentary is cautious, the stock may see muted movement as investors reassess growth prospects.

Miss

A miss on earnings could lead to a decline, with historical patterns indicating an average drop of around 5.90% following such outcomes.

Earnings Track Record

Preparation

What to Listen For

Call Prep

1Any updates on new product launches or partnerships that could drive revenue growth.
2Details on cost management strategies that could improve EPS in the coming quarters.
3Insights into market demand for Twist's products and how it compares to competitors.
4Management's outlook on future revenue growth and profitability targets.
5Responses to analyst questions regarding recent insider selling and its implications for investor confidence.

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Company Snapshot

Key Metrics to Watch

Earnings Per Share (EPS)

EPS is a crucial indicator of the company's profitability and financial health, helping investors gauge performance against expectations.

$-0.53

Revenue

Revenue reflects the company's ability to generate sales and is essential for assessing growth and market demand for its products.

$108M

Wall Street expectations, options signals, track record, and call prep available with Pro.

Original Pre-Earnings Preview

Context

Company Snapshot

Earnings Scorecard·Last 8Q

EPS Beat Streak

EPS Beat Rate

38%

Avg EPS Surprise

+5.33%

Avg Stock Reaction

-3.48%

Last Quarter Recap

Management Promises & Guidance

Expectations

Wall Street Expectations

Analysts expect Twist to report a loss of $-0.53 per share on revenues of $108 million for Q2-2026. The market is closely watching these figures to assess the company's growth trajectory.

Bull Case

If Twist can exceed the revenue expectations and show signs of improving margins, it could signal a turnaround in its financial performance, leading to a positive stock reaction.

Bear Case

Conversely, if the company fails to meet revenue expectations or reports a wider loss, it could raise concerns about its growth strategy and lead to a negative market reaction.

Key Metrics to Watch

Earnings Per Share (EPS)

$-0.53

EPS is a crucial indicator of the company's profitability and financial health, helping investors gauge performance against expectations.

Revenue

$108M

Revenue reflects the company's ability to generate sales and is essential for assessing growth and market demand for its products.

Expectations

Two Questions That Matter

The print will turn on these two things.

Will Twist's revenue meet or exceed the consensus estimate of $108 million?

Revenue performance is critical for assessing the company's growth and market demand, which will heavily influence investor sentiment.

What specific strategies is management implementing to improve EPS, currently estimated at $-0.53?

Understanding management's approach to improving profitability is essential for evaluating the company's future potential and operational efficiency.

Edge

What the Street Is Missing

Why consensus could be wrong

The Street may be underestimating Twist's potential for revenue growth due to its innovative product offerings and expanding market presence.

Supporting Evidence

Despite recent misses, Twist's technology pipeline suggests potential for significant revenue increases not reflected in current estimates.

The options market is pricing in a larger move than historical averages, indicating that traders expect a more substantial shift in stock price than the consensus suggests.

Key Risk

If Twist's revenue growth exceeds $108 million, it could challenge the current bearish sentiment and shift investor expectations.

Edge

Thesis-Break Levels

Pre-commit to what would confirm each case.

This quarter, the debate centers around whether Twist can demonstrate solid revenue growth and a path to profitability amid ongoing market challenges.

Bull Confirmed If

Revenue growth exceeding $108 million with a reduction in EPS loss to below $-0.50 would confirm the bull case.

Bear Confirmed If

A revenue miss below $107 million or an EPS loss greater than $-0.53 would confirm the bear case.

Pre-Earnings Positioning

Options Market

Implied Move

±15.73%

Historical Avg

±10.2%

Pricing rich

The options market is pricing in a significant move of about 15.73%, indicating that investors expect volatility around the earnings announcement.

Options are pricing ±15.7% while TWST has averaged ±10.2% over the last 8 prints — setup is pricing rich.

Detail

ATM IV

1.1%

30d HV

75.0%

Calls (18K)P/C Ratio: 0.40Puts (900)

Edge

Insider Activity

Open-market trades by officers, directors, and 10%+ holders over the trailing 90 days.

Bought

$0.00

0 sh

0 insiders

Sold

$1.2M

19,268 sh

2 insiders

Net

$1.2M

Net selling

Most Active Insiders· 6 open-market trades

Chief Executive OfficerLeproust Emily M.
$630,957.35

Preparation

Post-Print Playbook

Likely market behavior by outcome — not investment advice.

Beat & Raise

If Twist beats expectations, history suggests a positive stock reaction, averaging a 0.72% increase the following day, confirming a bullish outlook.

In-Line / Cautious

If results are in line with expectations but management's commentary is cautious, the stock may see muted movement as investors reassess growth prospects.

Miss

A miss on earnings could lead to a decline, with historical patterns indicating an average drop of around 5.90% following such outcomes.

Earnings Track Record

Preparation

What to Listen For

Call Prep

1Any updates on new product launches or partnerships that could drive revenue growth.
2Details on cost management strategies that could improve EPS in the coming quarters.
3Insights into market demand for Twist's products and how it compares to competitors.
4Management's outlook on future revenue growth and profitability targets.
5Responses to analyst questions regarding recent insider selling and its implications for investor confidence.